BioGlena™️
Beta Glucan Derived From Microalgae For immune Support
BioGlena™ is a natural whole Euglena Gracillis microalgae containing 55% linear 1,3 Beta-Glucan, complete proteins, and essential nutrients. BioGlena™ is a natural, solvent-free source, setting it apart from other beta-glucan products that require harsh extraction processes. BioGlena™ primes immune cells, enhancing and balancing natural immunity to respond stronger and faster to pathogens. BioGlena™ provides daily immune support and is suitable for individuals of all ages.
BioGlena™ is a reach source of Beta Glucan
Euglena gracilis is a single-cell microalga, living in most freshwater habitats. It naturally produces linear 1-3 beta-glucans called paramylon, which are stored as free-floating granules in the cell, and known for their immuno-modulatory functions.
Euglena grcaillis accumulates a large amount of beta-glucans within its cells and uses them as a major energy storage compound.
The algae also contain complete proteins, essential vitamins, and minerals.
BioGlena™ taken orally is easily digested in the stomach, effectively releasing the beta-glucans from within the algal matrix where they are picked up by immune cells in the intestine and transported to key sites in the body. This initiates a cascade of immune signaling and immune cell priming, helping to naturally strengthen the innate and adaptive immune system against pathogens.
Immune support with Beta-glucans
Beta glucan immune support mechanism
BETA GLUCANS INDUCE TRAINED IMMUNITY
Trained immunity is a newly identified immune mechanism describes a functional reprogramming of innate immune cells following exposure to stimuli, which leads to an enhanced response toward a second stimulus.
Beta-glucans are typical inducers of trained immunity, which can be induced in three phases:
1) Unstimulated immune cells, such as macrophages, bind Beta-glucans via the dectin-1 receptor and are thereby activated and undergo a functional epigenetic reprogramming and associated metabolic changes, preparing the cells for future encounters with pathogens.
2)The cells are resting (not active) but are trained (primed) and ready for action .
3) Trained/primed cells encounter a pathogen (or experimental pathogen mimic) and respond
more effectively and powerfully than non-trained/non-primed cells.
BioGlena™ induces trained immunity
The effect of BioGlena was evaluated in an in vitro study with human macrophages. The cells were incubated with BioGlena or neutral controls for 24 hours, followed by a five-day rest period. At the end of the resting period the cells were incubated with bacteria and viruses. The results demonstrated that macrophages exposed to BioGlena responded more effectively to the pathogens compared to controls .
PROPERTIES
COMPLIANCE
Vegan, NON-GMO,
Gluten free, Allergen free
SHELF LIFE
3 years
REGULATION
GRAS
APPLICATIONS
Capsules, Tablets, Gummies,
powder & functional food
FOOD INGREDIENT
Applicable to multiple food categories
RECOMMENDED DOSE
Dietary supplements - just 375 mg /daily*
Food – up to 450 mg per serving
More Resources
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Companies need to make their own determination regarding whether there is a substantiation for the claims for their finished products, taking into consideration product formulation, dosage and directions for use, and for ascertaining the proper use of this product with regard to applicable laws and regulations.
